Top 20 GP Prometric Exam Questions Doctors Should Know in 2026
Introduction
The Prometric Exam for General Practitioners is a key licensing assessment for physicians planning to work in the Gulf under authorities such as the Dubai Health Authority, Saudi Commission for Health Specialties, and Ministry of Health and Prevention.
The exam typically includes 150 clinical MCQs across internal medicine, pediatrics, obstetrics & gynecology, surgery, emergency medicine, and preventive medicine.
Below are 20 high-yield Prometric-style clinical questions that reflect the type of reasoning tested in the exam.
Question 1 — Cardiology
A 60-year-old man presents with crushing retrosternal chest pain radiating to the jaw for 30 minutes. ECG shows ST elevation in leads II, III, and aVF.
What is the first medication that should be administered?
A. Aspirin
B. Morphine
C. Metoprolol
D. Heparin
E. Nitroglycerin
Answer: Aspirin
Question 2 — Pulmonology
A 55-year-old smoker presents with progressive dyspnea and chronic cough. Spirometry shows:
What is the most likely diagnosis?
A. Asthma
B. COPD
C. Pulmonary fibrosis
D. Bronchiectasis
E. Sarcoidosis
Answer: COPD
Question 3 — Pediatrics
A 3-year-old child presents with barking cough, stridor, and hoarseness.
Most likely diagnosis?
A. Epiglottitis
B. Croup
C. Bronchiolitis
D. Asthma
E. Pneumonia
Answer: Croup
Question 4 — Obstetrics
A pregnant woman at 34 weeks presents with painless vaginal bleeding.
Most likely diagnosis?
A. Placental abruption
B. Placenta previa
C. Uterine rupture
D. Cervical polyp
E. Vasa previa
Answer: Placenta previa
Question 5 — Emergency Medicine
A patient presents with anaphylaxis after peanut ingestion.
What is the first-line treatment?
A. Antihistamines
B. Corticosteroids
C. Epinephrine IM
D. Salbutamol
E. Oxygen
Answer: Epinephrine IM
Question 6 — Endocrinology
A 50-year-old obese patient is diagnosed with type 2 diabetes.
First-line pharmacological treatment?
A. Metformin
B. Insulin
C. Sulfonylurea
D. GLP-1 agonist
E. DPP-4 inhibitor
Answer: Metformin
Question 7 — Infectious Disease
A patient presents with fever, neck stiffness, and photophobia. CSF analysis shows:
High neutrophils
Low glucose
High protein
Most likely diagnosis?
A. Viral meningitis
B. Bacterial meningitis
C. Fungal meningitis
D. Tuberculous meningitis
E. Encephalitis
Answer: Bacterial meningitis
Question 8 — Nephrology
A patient with diabetes develops persistent albuminuria.
Which medication slows progression of nephropathy?
A. Beta-blocker
B. ACE inhibitor
C. Calcium channel blocker
D. Loop diuretic
E. Digoxin
Answer: ACE inhibitor
Question 9 — Gastroenterology
A 45-year-old patient presents with epigastric pain relieved by food.
Most likely diagnosis?
A. Gastric ulcer
B. Duodenal ulcer
C. GERD
D. Pancreatitis
E. Gallstones
Answer: Duodenal ulcer
Question 10 — Hematology
A patient with fatigue has:
Most likely diagnosis?
A. Iron deficiency anemia
B. Vitamin B12 deficiency
C. Folate deficiency
D. Hemolytic anemia
E. Aplastic anemia
Answer: Iron deficiency anemia
Question 11 — Neurology
A patient presents with sudden unilateral weakness and slurred speech.
Most important first investigation?
A. MRI brain
B. CT brain
C. EEG
D. Lumbar puncture
E. Carotid Doppler
Answer: CT brain
Question 12 — Rheumatology
A patient presents with joint pain, malar rash, and photosensitivity.
Most likely diagnosis?
A. Rheumatoid arthritis
B. Systemic lupus erythematosus
C. Osteoarthritis
D. Gout
E. Psoriatic arthritis
Answer: SLE
Question 13 — Dermatology
A patient presents with silvery scales on extensor surfaces.
Most likely diagnosis?
A. Psoriasis
B. Eczema
C. Tinea corporis
D. Lichen planus
E. Impetigo
Answer: Psoriasis
Question 14 — Pediatrics
A 6-month-old infant has episodes of intense crying with drawing up of legs.
Most likely diagnosis?
A. Appendicitis
B. Intussusception
C. Hernia
D. Gastroenteritis
E. Colic
Answer: Intussusception
Question 15 — Obstetrics
Most common cause of postpartum hemorrhage?
A. Uterine atony
B. Retained placenta
C. Uterine rupture
D. Cervical tear
E. Coagulopathy
Answer: Uterine atony
Question 16 — Cardiology
A patient with atrial fibrillation requires stroke prevention.
Best long-term therapy?
A. Aspirin
B. Warfarin / DOAC
C. Beta blockers
D. Digoxin
E. Amiodarone
Answer: Anticoagulation (Warfarin/DOAC)
Question 17 — Pulmonology
Best initial treatment for acute asthma exacerbation?
A. Oral steroids
B. Salbutamol inhalation
C. Antibiotics
D. Antihistamines
E. Montelukast
Answer: Salbutamol inhalation
Question 18 — Surgery
A patient presents with right lower quadrant pain and fever.
Most likely diagnosis?
A. Cholecystitis
B. Pancreatitis
C. Appendicitis
D. Diverticulitis
E. IBS
Answer: Appendicitis
Question 19 — Preventive Medicine
Best screening test for colorectal cancer?
A. CT scan
B. Colonoscopy
C. Ultrasound
D. X-ray
E. MRI
Answer: Colonoscopy
Question 20 — Emergency Medicine
A trauma patient presents with hypotension and tachycardia.
Most appropriate initial management?
A. CT scan
B. Blood transfusion
C. IV fluids
D. Antibiotics
E. Surgery
Answer: IV fluids
